01 -
Gather all ingredients and prepare them for the recipe.
02 -
Preheat the oven to 450°F (230°C). Line a rimmed baking sheet with aluminum foil and lightly spray with cooking spray.
03 -
Peel shrimp, leaving tails intact. Use a paring knife to cut lengthwise down the vein side of each shrimp, cutting almost but not all the way through. Remove the vein and butterfly the shrimp by gently pressing them apart.
04 -
In a bowl, combine shrimp, wine, olive oil, oregano, 1 tablespoon parsley, 1 tablespoon garlic, 1 teaspoon lemon zest, ¼ teaspoon crushed red pepper, and salt. Toss to coat evenly and let stand at room temperature for 10 minutes.
05 -
In a separate small bowl, combine panko, Parmesan cheese, 2 tablespoons melted butter, the remaining 1 tablespoon parsley, remaining 1 tablespoon garlic, remaining 1 teaspoon lemon zest, and ¼ teaspoon crushed red pepper. Stir until well mixed.
06 -
Remove shrimp from the marinade and place them cut side up, about 2 inches apart, on the prepared baking sheet. Top each shrimp with about 2 teaspoons of the panko mixture, pressing lightly to adhere.
07 -
Bake the shrimp in the preheated oven until cooked through, about 8 to 10 minutes. Without opening the oven, switch to broil and cook until the topping is golden brown and crispy, about 1 to 2 minutes.
08 -
In a small bowl, stir together lemon juice, remaining 1 tablespoon melted butter, and any accumulated juices from the baking sheet.
09 -
Transfer shrimp to a serving platter, drizzle evenly with the prepared lemon-butter mixture, and garnish with parsley. Serve hot with lemon wedges.